| See program & abstracts
  	
	      	
        	
        		
        		   Thursday, September 23, 2021        	    
        	 
        	
    	      	
    	        	
    	          		| Time | Event | (+) |  
        	          	| 08:00 - 08:35 | Welcoming participants |  |  
        	          	| 08:35 - 08:45 | Welcome Speech - Pr Jacques Lebreton, Université de Nantes |  |  
        	          	| 08:45 - 09:00 | Opening allowance - Pr Olivier GRASSET, VP Recherche et science ouverte, Université de Nantes |  |  
        	          	| 09:00 - 09:15 | Introduction - Madame SOULTANI VIGNERON Samia, Vice-présidente du Conseil régional des Pays de la Loire |  |  
        	          	| 09:15 - 12:20 | SESSION 1 : Chairman - Pr Jacques LEBRETON, Université de Nantes |  |  
        	          	| 09:15 - 10:15 | “A Brief History of PPIs”  - Dr Philippe ROCHE, Aix-Marseille Université |  |  
        	          	| 10:15 - 10:45 | Coffee break |  |  
        	          	| 10:45 - 11:30 | RhoA PPI Axe Results  - Dr Gervaise LOIRAND, Université de Nantes |  |  
        	          	| 11:30 - 11:55 | "Design of antiviral drugs for bronchiolitis virus using a novel therapeutic target" - Silva KHODJOYAN, Doctorante, Université Paris-Saclay |  |  
        	          	| 11:55 - 12:20 | Photoactivated ligands for the control of ion channel activity" - Dr Jérôme MONTNACH, Chercheur postdoctoral, Université de Nantes |  |  
        	          	| 12:20 - 13:45 | Lunch cocktail |  |  
        	          	| 13:45 - 17:35 | SESSION 2 : Chairman - Pr Sylvain COLLET, Université de Nantes |  |  
        	          	| 13:45 - 14:45 | "NMR-guided and fragment-based design of protein-protein interaction inhibitors. Application to CK2 kinase" - Dr Isabelle KRIMM, Université Lyon 1 |  |  
        	          	| 14:45 - 15:30 | BCL-xL PPI Axe Results - Dr Stéphane TELETCHEA, Université de Nantes |  |  
        	          	| 15:30 - 16:00 | Coffee break |  |  
        	          	| 16:00 - 16:45 | IL-15 PPI Axe Results - Dr Erwan MORTIER, Université de Nantes |  |  
        	          	| 16:45 - 17:10 | "Synthesis and Biological assessments for RhoGTPases’ inhibition" - Thomas RIVIERE, Assistant ingénieur, Université de Nantes |  |  
        	          	| 17:10 - 17:35 | "Synthesis and Evaluation of Small Molecule Inhibitors of Interleukin (IL)-15: Towards IL-15 vs IL-2 Selectivity" - Jimmy SMADJA, Doctorant, Université de Nantes |  |  
        	
        		
        		   Friday, September 24, 2021        	    
        	 
        	
    	      	
    	        	
    	          		| Time | Event | (+) |  
        	          	| 08:30 - 12:00 | SESSION 3 : Chairman - Pr Jean-Yves LE QUESTEL, Université de Nantes |  |  
        	          	| 08:30 - 09:30 | "Structure-guided design of MCL-1 inhibitors” - Pr Jana SOPKOVA-DE OLIVEIRA SANTOS, Université de Caen Normandie |  |  
        	          	| 09:30 - 10:15 | Hsp90 PPI Axe Results - Pr Patrice LE PAPE, Université de Nantes |  |  
        	          	| 10:15 - 10:45 | Coffee break |  |  
        	          	| 10:45 - 11:10 | "Design of anti-fungal agents against Candida albicans using in silico techniques" - Mohammad ASAD, Doctorant, Université de Nantes |  |  
        	          	| 11:10 - 11:35 | "Synthesis & evaluation of Bcl-2 family proteins modulating compounds for cancer treatment" - Dr Nicolas GUEDENEY, Chercheur postdoctoral, Université de Rennes 1 |  |  
        	          	| 11:35 - 12:00 | "Binding of the Cancer-Related TCTP Protein to Mcl- 1/Bcl-xL Requires and Triggers an Order-to-Disorder Transition to Make its BH3 Region Accessible" - Dr Ewen LESCOP, Chercheur, Université Paris-Saclay |  |  
        	          	| 12:00 - 13:30 | Lunch cocktail |  |  
        	          	| 13:30 - 16:00 | SESSION 4 : Chairman - Dr Arnaud TESSIER, Université de Nantes |  |  
        	          	| 13:30 - 14:30 | “Conception of Natural-Inspired Small-Molecule Inhibitors of Bcl-2 Family Proteins” - Dr Fanny ROUSSI, ICSN, Université Paris-Saclay |  |  
        	          	| 14:30 - 15:15 | Rad 51 PPI Axe Results - Pr Fabrice FLEURY, UFIP, Université de Nantes |  |  
        	          	| 15:15 - 15:40 | "Strengths, weaknesses and bottlenecks in new drug design and validation" - Dr Stéphane TELETCHEA, Université de Nantes |  |  
        	          	| 15:40 - 16:00 | Coffee break |  |  
        	          	| 16:00 - 16:30 | Closing of the Symposium and award ceremony for the best oral communication |  |  |